Publications
2024
Bagnolini G., Poppi L., Previtali V., Ferrandi G., Rinaldi F., Girotto S., Hirsch A.K.H., Roberti M., Cavalli A.
A journey through targeting BRCA2-RAD51 protein-protein interaction to establish synthetic lethality as paradigm for anticancer drug discovery
National Congress of the Italian Chemistry Society 2024
Poster
Conference
2024
Rinaldi F., Bernetti M., Bresciani V., Girotto S., Cavalli A.
An integrated structural approach reveals novel insights on the BRCA2 - RAD51 interaction
EMBO Practical Course on Small Angle Neutron and X-ray Scattering from biomacromolecules in solution
Poster
Conference
2024
Balboni B., Marotta R., Rinaldi F., Milordini G., Varignani G., Girotto S., Cavalli A.
An integrative structural study of the human full-length RAD52 at 2.2 Å resolution
Communications Biology, vol. 7, (no. 1)
2024
Ahmed H., Lopez H., Boselli F., Tarricone G., Vercellino S., Costantini P.E., Castagnola V., Veronesi M., Benfenati F., Danielli A., Boselli L., Pompa P.P.
Biomimetic Plasmonic Nanophages by Head/Tail Self-Assembling: Gold Nanoparticle/Virus Interactions
ACS Nano, vol. 18, (no. 32), pp. 21302-21315
Article
Journal
2024
Sgroi S., Romeo E., Albanesi E., Piccardi F., Catalano F., Debellis D., Bertozzi F., Reggiani A.
Combined in vivo effect of N-acylethanolamine-hydrolyzing acid amidase and glycogen synthase kinase-3β inhibition to treat multiple sclerosis
Biomedicine and Pharmacotherapy, vol. 175
2024
Brindani N., Vuong L.M., La Serra M.A., Salvador N., Menichetti A., Acquistapace I.M., Ortega J.A., Veronesi M., Bertozzi S.M., Summa M., Girotto S., Bertorelli R., Armirotti A., Ganesan A.K., De Vivo M.
Discovery of CDC42 Inhibitors with a Favorable Pharmacokinetic Profile and Anticancer In Vivo Efficacy
Journal of Medicinal Chemistry, vol. 67, (no. 12), pp. 10401-10424
2024
Balboni B., Marotta R., Rinaldi F., Milordini G., Varignani G., Girotto S., Cavalli A.
Human full-length RAD52 at 2.2 Å resolution: an integrative structural biology study
Communications Biology
Article
Journal
2024
Romaldini A., Spano R., Veronesi M., Grimaldi B., Bandiera T., Sabella S.
Human Multi-Lineage Liver Organoid Model Reveals Impairment of CYP3A4 Expression upon Repeated Exposure to Graphene Oxide
Cells, vol. 13, (no. 18)
Article
Journal
2024
Romeo E., Saccoliti F., Andonaia A., Allegretta C., Laselva O., Falchi F., Occello R., Liessi N., Armirotti A., Girotto S., Pastorino C., Pedemonte N., Bandiera T., Bertozzi F.
Mechanism of action and binding site characterization of corrector ARN23765 via Photo-Affinity Labeling (PAL) approach in live cells
19th ECFS Basic Science Conference
Poster
Conference
2024
Rinaldi F., Girotto S.
Structure-based approaches in synthetic lethality strategies
Current Opinion in Structural Biology, vol. 88
Review
Journal
2023
Myers S. H., Poppi L., Rinaldi F., Veronesi M., Ciamarone A., Previtali V., Bagnolini G., Schipani F., Ortega Martínez J. A., Girotto S., Di Stefano G., Farabegoli F., Walsh N., De Franco F., Roberti M., Cavalli A.
An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer
European Journal of Medicinal Chemistry
2023
Demuro S., Di Martino R.M.C., Sauvey C., Tripathi S.K., Ortega J. A., Russo D., Penna I., Myers S. H., Bandiera T., Girotto S., Abagyan R., Cavalli A.
Design and synthesis of triple protein kinase inhibitors: paving the way towards novel CNS tools to reverse the aberrant tau phosphorylation
ACS Spring 2023 meeting
Poster
Conference
2023
Brindani N., Vuong L.M., Acquistapace I.M., La Serra M.A., Ortega J.A., Veronesi M., Bertozzi S.M., Summa M., Girotto S., Bertorelli R., Armirotti A., Ganesan A.K., De Vivo M.
Design, Synthesis, In Vitro and In Vivo Characterization of CDC42 GTPase Interaction Inhibitors for the Treatment of Cancer
Journal of Medicinal Chemistry, vol. 66, (no. 8), pp. 5981-6001
2023
Anselmi M., Bellina F., Quaia R., Panosetti M., Veronesi M., Girotto S., Bertozzi F., Duca M., Bandiera T.
DISCOVERY OF SMALL-MOLECULE INHIBITORS OF MICRORNA-21 BIOGENESIS
IX EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry
Poster
Conference
2023
Rinaldi F., Bernetti M., Bresciani V., Girotto S., Cavalli A.
Dissecting the BRCA2 - RAD51 interaction by integrating computational and experimental biophysics
EMBO Practical Course Integrative modelling of protein interactions
Poster
Conference