IIT Publications Search

Publications
2025
Rinaldi F., Balboni B., Varignani G., Milordini G., Marotta R., Girotto S., Cavalli A.
An integrative structural study of RAD52, an emerging target in anticancer drug discovery
XXIX National Meeting on Medicinal Chemistry of the Italian Chemistry Society
Poster Conference
2025
Rinaldi F., Balboni B., Girotto S., Cavalli A.
An integrative structural study of RAD52, an emerging target in anticancer drug discovery
XXIX National Meeting on Medicinal Chemistry of the Italian Chemistry Society
Poster Conference
2025
Milordini G., Zacco E., Armaos A., Di Palma F., Masi M., Gilodi M., Rupert J., Broglia L., Varignani G., Oneto M., Scotto M., Marotta R., Girotto S., Cavalli A., Tartaglia G.G.
Computationally-designed aptamers targeting RAD51-BRCA2 interaction inhibit RAD51 nuclear recruitment
bioRxiv
DOI 10.1101/2025.01.20.633558
Article E-print Archive
2025
Rinaldi F., Balboni B., Marotta R., Girotto S., Cavalli A.
Elucidating RAD52 architecture through an integrated structural biology approach
51st Meeting of the Italian Crystallographic Association
Poster Conference
2025
Mirra G., Cursi L., Veronesi M., Boselli L., Pompa P.P.
Gold nanozymes for efficient degradation of organic dye pollutants: outperforming natural enzymes
Nanoscale
DOI 10.1039/d4nr05137h
Article Journal
2025
Bresciani V., Rinaldi F., Franco P., Girotto S., Cavalli A., Langer J. D., Masetti M., Bernetti M.
Integrating computational and experimental biophysics reveals novel insights into the RAD51-BRC4 interaction
BiorXiv
DOI 10.1101/2025.03.07.642044
Article E-print Archive
2025
Masi M., Poppi L., Previtali V., Nelson S.R., Wynne K., Varignani G., Falchi F., Veronesi M., Albanesi E., Tedesco D., De Franco F., Ciamarone A., Myers S.H., Ortega J.A., Bagnolini G., Ferrandi G., Farabegoli F., Tirelli N., Di Stefano G., Oliviero G., Walsh N., Roberti M., Girotto S., Cavalli A.
Investigating synthetic lethality and PARP inhibitor resistance in pancreatic cancer through enantiomer differential activity
Cell Death Discovery, vol. 11, (no. 1)
DOI 10.1038/s41420-025-02382-3
Article Journal
2025
Codino A., Spagnoletti L., Olobardi C., Cuomo A., Santos-Rosa H., Palomba M., Margaroli N., Girotto S., Scarpelli R., Luan S.-L., Crocco E., Bianchini P., Bannister A.J., Gustincich S., Kouzarides T., Rizzo R., Barbieri I., Cremisi F., Vignali R., Pandolfini L.
METTL9 sustains vertebrate neural development primarily via non-catalytic functions
Nature Communications, vol. 16, (no. 1)
DOI 10.1038/s41467-025-62414-5
Article Journal
2025
Codino A., Spagnoletti L., Olobardi C., Cuomo A., Santos-Rosa H., Palomba M., Margaroli N., Girotto S., Scarpelli R., Lu Luan S., Crocco E., Bianchini P., Bannister A.J., Gustincich S., Kouzarides T., Rizzo R., Barbieri I., Cremisi F., Vignali R., Pandolfini L.
METTL9 sustains vertebrate neural development primarily via non-catalytic functions
Nature Communications
Article in Press Journal
2025
Manju Sudheer M., Fazli A., Sganga S., Tirelli N., Carzino R., Veronesi M., Khabarov K., Athanassiou A., Fragouli D.
Poly(lactic acid) nanoplastics through laser ablation: establishing a reference model for mimicking biobased nanoplastics in aquatic environments
Environmental Science: Nano
DOI 10.1039/d4en00891j
2025
Rinaldi F., Bresciani V., Franco P., Veronesi M., Bernetti M., Masetti M., Langer J., Cavalli A., Girotto S.
Probing the BRC repeats RAD51 interaction by integrating computational and experimental biophysics
The 49th FEBS Congress
Poster Conference
2025
Di Martino R.M.C., Russo D., Penna I., Demuro S., Dalle Vedove A., Spagnuolo R., Ottonello G., Bertozzi S.M., Summa M., Desantis J., Valeri A., Pruccoli L., Tripathi S.K., Tarozzi A., Storici P., Girotto S., Bertorelli R., Armirotti A., Cruciani G., Bandiera T., Cavalli A., Bottegoni G.
Rational optimization of D3R/GSK-3β dual target-directed ligands as potential treatment for bipolar disorder: Design, synthesis, X-ray crystallography, molecular dynamics simulations, in vitro ADME, and in vivo pharmacokinetic studies
European Journal of Medicinal Chemistry, vol. 297
DOI 10.1016/j.ejmech.2025.117899
2025
Romeo E., Saccoliti F., Andonaia A., Allegretta C., Occello R., Pastorino C., Pedemonte N., Girotto S., Falchi F., Laselva O., Bandiera T., Bertozzi F.
Target identification with live-cell photo-affinity labelling and elucidation of the mechanism of action of the CFTR corrector ARN23765
EFMC-ISCB
Poster Conference
2025
Rinaldi F., Bernetti M., Bresciani V., Veronesi M., Masetti M., Girotto S., Cavalli A.
The mechanistic understanding of the BRCA2-RAD51 interaction: an integrated structural biophysics study
Mammalian DNA Repair Gordon Research Conference: DNA Repair: Fundamental Mechanisms and Human Biology
Poster Conference
2025
Rinaldi F., Girotto S.
Understanding how structure shapes the architecture of homologous recombination
Current Opinion in Structural Biology
Review Journal

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